KHRC Works in Progress Seminars (WIPs)

KHRC Works in Progress (WIPs) occur every other Monday via Zoom at 10am-11am.  They are an opportunity for our members to present work and ideas in order to get feedback and comments.  If you are interested in learning more about our work, please feel free to join us for these WIPs.  Please contact Erica Day ([email protected]) for more information about our WIPs and participating.

Monday, April 22, 2024

Presenter: Simon Ascher

Topic: Statistical approaches to summarizing prognostic information across kidney biomarkers in SPRINT CKD

Monday, April 15, 2024

Presenter: Teresa Chen

Topic: Potential grant idea discussion 

Monday, April 8, 2024

Presenter: Kenny Hubbell

Topic: Proteomic predictors of rehospitalization, mortality, and diuretic resistance in acute decompensated heart failure

Monday, March 25, 2024

Presenter: Mike Shlipak, MIchelle, Estrella, Erica Day

Topic: How does reseach funding work?

Monday, March 11, 2024

Presenter: Anthony Muiru

Topic: Poster draft and SEARCH data

Monday, March 4, 2024

Presenter: Michelle Estrella 

Topic: new data presentation 

Monday, February 26, 2024

Presenter: Rebecca Scherzer

Topic: Comparison of biomarker selection methods in prediction of post hospital outcomes

Monday, February 12, 2024

Presenter: Julio Lamprea Montealegre 

Topic: CKD detection and treatment to prevent cardiovascular disease

Monday, January 22, 2024

Presenter: Jesse Ikeme

Topic: eGFR monitoring and SGLT2i discontinuation in the VA

Monday, January 8, 2024

Presenter: Michelle Estrella 

Topic: Rural-urban disparities in CKD/CVD care and impact on outcomes 


Monday, December 11, 2023

Presenter: Vasantha Jotwani and Scott Bauer 

Topic: SOMMA Kidney R01 grant proposal 

Monday, December 4, 2023

Presenter: Simon Ascher 

Topic: K23 Summary Statement review 

Monday, November 13, 2023

Presenter: Group discussion 

Topic: ASN Debrief 

Monday, October 30, 2023

Presenter: Tanya Jones

Topic: ASN practice talk

Monday, October 23, 2023

Presenter: Meyeon Park and Meghana Eswarappa

Topic: Racial disparities in ADPKD

Monday, October 16, 2023

Presenter: Teresa Chen and Jesse Ikeme

Topic: ASN Kidney Week poster feedback

Monday, September 11, 2023

Presenter: Anoop Sheshadri

Topic: K23 application 

Monday, August 28, 2023

Presenter: Michael Shlipak

Topic: new R01 award- Environmental Metal Toxicity and Kidney Tubule Measures in Diverse Populations

Monday, August 21, 2023

Presenter: Kathleen Cui

Topic: Research project 

Monday, August 14, 2023

Presenter: Mitra Jasmidian and Simon Ascher 

Topic: SPRINT data 

Monday, August 7, 2023

Presenter: Meyeon Park

Topic: PKD projects

Monday, July 31, 2023

Presenter: Teresa Chen

Topic: Grant application summary statement 

Monday, June 12, 2023

Presenter: Jesse Ikeme

Topic: Results on SGLT2 inhibitor discontinuation

Monday, June 5, 2023

Presenter: Michelle Estrella

Topic: Bayer proposal - Phase II

Monday, May 15, 2023

Presenter: Edouard Fu

Topic: Timing of dialysis iniation 

Monday, May 8, 2023

Presenter: Teresa Clifton 

Topic: Potential original restrospective cohort study 

Monday, April 17, 2023

Presenter: Rebecca Scherzer

Topic: A Survey of Bayesian Applications 

Monday, April 3, 2023

Presenter: Simon Ascher 

Topic: SPRINT data 

Monday, March 20, 2023

Presenter: Mason Lai

Topic: Draft manuscript on PARIS cohort 

Monday, February 27, 2023

Presenter: Chi Chu and Anthony Muiru

Topic: Use of alternate databases - kidney transplant waiting times

Monday, February 6, 2023

Presenter: Merve Postalcioglu

Topic: research project progress 

Monday, January 23, 2023

Presenter: Rebecca Scherzer

Topic: Statistical faux pas - BMJ article

Monday, January 9, 2023

Presenter: Michelle Estrella

Topic: C3 project- Phase 2 multicenter trial 

Monday, December 12, 2022

Presenter: Anoop Sheshadri 

Topic: VA CDA application 

Monday, November 21, 2022

Presenter: group discussion 

Topic: ASN Kidney Week conference debrief

Monday, October 24, 2022

Presenter: Mitra Jamshidian

Topic:  research progress update 

Monday, October 3, 2022

Presenter: Teresa Chen

Topic: Evaluating the performance and use of cystatin C in the inpatient setting

Monday, August 29, 2022

Presenter: team meeting 

Topic: check in meeting with all members

Monday, August 22, 2022

Presenter: Scott Bauer

Topic: Feedback on new grant submission 

Monday, August 15, 2022

Presenter: Simon Ascher 

Topic: Incorporating personalized risk estimates and outcome preferences into blood pressure target decisions

Monday, August 8, 2022

Presenter: Merve Postalcioglu

Topic: CARDIA urine biomarkers and eGFR

Monday, July 11, 2022

Presenter: Anthony Muiru

Topic: Practice talk for Harold Amos grant



Monday, June 13, 2022

Presenter: Chi Chu and Anthony Muiru

Topic: KFRE

Monday, June 6, 2022

Presenter: Debbie Chen 

Topic: Obesity-CysC proposal 

Monday, May 23, 2022

Presenter: M Bilal S Khan (UAB)

Topic: Presentation of data on urine biomarker paper using CARDIA data

Monday, May 16, 2022

Presenter: Michael Shlipak 

Topic: New data presentation 

Monday, May 9, 2022

Presenter: Michelle Estrella, Anthony Muiru, Erin Madden 

Topic: Dismantling Structural Racism in Medicine, Part II

Monday, May 2, 2022

Presenter: Sarah Schrauben (UPenn)

Topic: Aims for future R01 submission 

Monday, April 11, 2022

Presenter: Michelle Estrella, Anthony Muiru, Erin Madden 

Topic: Dismantling Structural Racism in Medicine, Part I

Monday, April 4, 2022

Presenter: Scott Bauer

Topic: Aims for new R01 submission

Monday, March 28, 2022

Presenter: Simon Ascher and Jon Amatrdua 

Topic: SPRINT cardiac-kidney biomarker project

Monday, March 21, 2022

Presenter: Michelle Estrella 

Topic: NSAID R01 grant revision 

Monday, March 14, 2022

Presenter: Chi Chu

Topic: K12 and research plans 

Monday, February 28, 2022

Presenter: Teresa Chen

Topic: REGARDS blood biomarkers and mortality

Monday, February 21, 2022


Monday, February 14, 2022

Presenter: Priya Joshi

Topic: Research project ideas 

Monday, February 7, 2022

Presenter: Julio Lamprea Montealegre

Topic: Race and ethnic differences in cardiac and kidney protective therapies utilization 

Monday, January 31, 2022

Presenter: Michelle Estrella

Topic: Feedback on grant aims

Monday, January 24, 2022

Presenter: Anoop Sheshadri

Topic: Discussion of new biomarker results from LIFE-KIDNEY



Monday, January 10, 2022

Presenter: Rebecca Scherzer

Topic: Discussion of "Polygenic Risk Scores for Kidney Function and Their Associations with Circulating Proteome, and Incident Kidney Diseases"


Monday, December 13, 2021

Presenter: Mike Shlipak

Topic: Aims for new R01 proposal

Monday, December 6, 2021

Presenter: Scot Bauer

Topic:TAME aims

Monday, November 29, 2021

Presenter: Jennifer Lees (University of Glasgow)

Topic: UK Biobank and some of her work in this cohort

Monday, November 22, 2021

Presenter: Scot Bauer

Topic: Aims for an ancillary R01

Monday, November 15, 2021

Presenter: Debbie Chen

Topic: eGFRdiff and incident heart failure in CRIC

Monday, November 1, 2021

Presenter: Michael Shlipak and Michelle Estrella

Topic: ICAN Project (Adoption of Inpatient Cystatin C Testing for Hospitalized Veterans to Improve Patient Safety)

Monday, October 25, 2021

Presenter: Anoop Sheshadri, Simon Ascher, and Michael Shlipak

Topic: ASN poster feedback

Monday, October 18, 2021

Presenter: Anthony Muiru

Topic: Aims presentation on grant proposal

October 11, 2021


Monday, October 4, 2021

Presenter: Michelle Odden and Carmen Peralta 

Topic: Nursing home study 

Monday, September 27, 2021

Presenter: Jonathan Amatruda and Anthony Muiru

Topic: ASN poster and presentation feedback

Monday, September 20, 2021

Presenter: Group discussion

Topic: Brainstorming on collaborating during the virtual ASN Kidney Week 2021

Monday, September 13, 2021

Presenter: Simon Ascher

Topic: KL2 Aims

September 6, 2021


Monday, August 30, 2021

Presenter: Scott Bauer

Topic: Preliminary data from the LURN study

Monday, August 23, 2021

Presenter: Julio Lamprea Montealegre

Topic: KHRC registry and utilization of cardio renal meds in the VA

Monday, August 16, 2021

Presenter: Michelle Estrella and Julio Lamprea Montealegre

Topic: : LVAD grant idea

Monday, August 9, 2021

Presenter: Lekha Tummalapalli

Topic: : K23 application

August 2nd, 2021


Monday, July 26, 2021

Presenter: Kristienne Edrosolan

Topic: : Mediation of associations between clinical risk factors and eGFR change by urine biomarkers in women living with HIV

Monday, July 19, 2021

Presenter: Michael Shlipak

Topic: : LIFE data

Monday, June 28, 2021

Presenter: Meyeon Park

Topic: : PKD grant

Monday, June 21, 2021

Presenter: Chi Chu

Topic: : Project looking at variation in eGFR at nephrology referral between health systems

Monday, June 14, 2021

Presenter: Lindsay Miller

Topic: : Grant aims discussion 

Monday, May 24th, 2021

Presenter: Debbie Chen

Topic: : CRIC Data

Monday, May 17th, 2021

Presenter: Diana Kwong

Topic: : Revised K23 Aims

Monday, May 10th, 2021

Presenter: Michelle Estrella

Topic: : Updates to C3 project

Monday, May 3rd, 2021

Presenter: Julio Lamprea Montealegre

Topic: : Cholesterol lowering targets in CKD

Monday, April 26th, 2021

Presenter: Anoop Sheshadri

Topic: : Prehabilitation for older patients treated with dialysis prior to kidney transplantation

Monday, April 19th, 2021

Presenter: Jonathan Amatruda

Topic: Association of multiple urine biomarkers and incident CKD in non-diabetics across 3 cohorts (ARIC, MESA, and REGARDS).

Monday, April 12th, 2021

Presenter: Lekha Tummalapalli

Topic: Quasi-experimental study designs

Monday, April 5th, 2021

Presenter: Rebecca Scherzer, PhD

Topic: Disscusion on: 

Haneuse S, Arterburn D, Daniels MJ. Assessing Missing Data Assumptions in EHR-Based Studies: A Complex and Underappreciated Task. JAMA Netw Open. 2021;4(2):e210184. doi:10.1001/jamanetworkopen.2021.0184

Monday, March 29th, 2021

Presenter: TBD

Topic: TBD

Monday, March 22nd, 2021

Presenter: Debbie Chen

Topic: Cystatin C-based CKD reclassification and outcomes among patients with cancer

Monday, March 15th, 2021

Presenter: Michelle Estrella and Michael Shlipak

Topic: HIV R01 resubmission 

Monday, March 8th, 2021

Presenter: Julio Lamprea Montealegre

Topic:Leveraging implementation science to improve kidney care

MARCH 1st, 2021


Monday, February 22nd, 2021

Presenter: Erin Madden

Topic:Joint longitudinal and time-to-event models, with example application in NA-Accord (HIV+ population)



Monday, February 8th, 2021

Presenter: Simon Ascher

Topic: Estimating lifetime treatment benefits of intensive BP lowering in persons with CKD

Monday, February 1st, 2021

Presenter: Debbie Chen

Topic: New project ideas 

Monday, January 25th, 2021

Presenter: Diana Kwong

Topic: K23 Aims feedback



Monday, January 11th, 2021

Presenter: Chi Chu

Topic: K23 application feedback



Monday, December 21st, 2020

Presenter: Mason Lai

Topic: Feedback on manuscript on dialysis access usage in recipients of living donor kidney transplants

Monday, December 14th, 2020

Presenter: Anoop Sheshadri

Topic: Feedback on upcoming KL2 grant

Monday, December 7th, 2020

Presenter: Michelle Estrella

Topic: Grant review summary on recent scored R01

Monday, November 30th, 2020


Monday, November 23rd, 2020

Presenter: Michael Shlipak

Topic: Aims on new EMPA grant proposal 

Monday, November 16th, 2020

Presenter: Simon Ascher

Topic: Data presentation on SPRINT CKD study evaluating kidney biomarker associations with serious adverse events (SAEs) during antihypertensive treatment

Monday, November 9th, 2020

Presenter: Anthony Muiru and Erin Madden

Topic: NA-ACCORD data

Monday, November 2nd, 2020

Presenter: Julio Lamprea Montealegre

Topic: Avanced glycation end products and kidney function decline in the Multi-Ethnic Study of Atherosclerosis

Monday, October 26th, 2020

Presenter: Scott Bauer

Topic: Study design and aims for a translational grant to define age-related changes in mitochondrial content and protein expression in male bladder and prostate tissue

Monday, October 19th, 2020


Monday, October 12th


Monday, October 5, 2020

Presenter: Multiple speakers in group

Topic: ASN Kidney Week Poster presentations

Monday, September 28th


Monday, September 21, 2020

Presenter: Sri Lekha Tummalapalli

Topic: Preliminary data and ideas on "Neighborhood-level Social Risk Factors and Dialysis Quality"

Monday, September 14, 2020

Presenter: Jonathan Amatruda

Topic: Feedback on approach for new heart failure project


Monday, August 31, 2020

Presenter: Bob Roshanravan

Topic: Feedback on R01 aims

Monday, August 24, 2020

Presenter: Michelle Estrella and Mike Shlipak

Topic: CKD Cascade of Care (C3) Initiative project update

Monday, August 17, 2020

Presenter: Jesse Ikeme

Topic: CKD urine biomarkers manuscript draft

Monday, August 10, 2020

Presenter: Michael Shlipak

Topic: Grand Rounds practice talk: Because Creatinine is Just Not Good Enough: The Clinical Case for Cystatin C

Monday, July 27, 2020

Presenter: Chi Chu

Topic: K23 aims about implementation of risk reporting to promote better risk stratification for referral to nephrology

Monday, July 20, 2020

Presenter: Group meeting

Topic: General group meeting

Monday, July 13, 2020

Presenter: Scott Bauer

Topic: Grand Rounds practice talk: Lower Urinary Tract Symptoms: Time to Reframe as a Syndrome of Aging?

Monday, July 6, 2020

Presenter: Scott Bauer

Topic: Using VA data to define safe ranges for post-void residual - early brainstorming session

Monday, June 29, 2020

Presenter: All group discussion

Topic: COVID-19 project brainstorming

Monday, June 22, 2020

Presenter: Rebecca Scherzer, Simon Ascher, and Mike Shlipak

Topic: Mediation models

Monday, June 15, 2020

Presenter: Julio Lamprea Montealegre

Topic: project at the VA on SGLT2i and GLP1-RA

Monday, June 8, 2020

Presenter: Simon Ascher

Topic: K23 Aims

Monday, May 18, 2020

Presenter: Jonathan Amatruda 

Topic: alpha-1 data and abstract

Monday, May 11, 2020

Presenter: Meyeon Park

Topic: Ancillary study proposal to APOLLO study

Monday, May 4, 2020

Presenter: Erin Madden

Topic: VA Data and data needs assessment for KHRC

Monday, April 27, 2020

Presenter: Julio Lamprea Montealegre

Topic: Dataset on ambulatory pulmonary artery pressure monitoring using the cardiomems device

Monday, April 20, 2020

Presenter: Michael Shlipak

Topic: HIV R01 renewal application 

Monday, April 6, 2020

Presenter: Chi Chu and Delphine Tuot

Topic: Optum Data project

Monday, March 23, 2020

Presenter: TBD

Topic: TBD

Monday, March 9, 2020

Presenter: Michael Shlipak, MD

Topic: Building a research career and the value of working in collaboration

Monday, February 24, 2020


Monday, October 7 , 2019

Presenter: Ani Chilingirian

Topic: ASN Kidney Week Oral Presentation

Monday, September 23, 2019

Presenter: Meyeon Park

Topic: PKD Foundation grant resubmission

Monday, September 9, 2019

Presenter: Anthony Muiru

Topic: K23 Aims

Monday, August 26, 2019

Presenter: Carmen Peralta

Topic: Review of Cricket Health

Monday, July 29, 2019


Monday, July 15, 2019

Presenter: Cythnia Delgado

Topic: Markers of CKD Mineral Bone Disorder as Targets to Address Physical Dysfunction and Sarcopenia (discussion on R01 proposal aims)

Monday, July 1, 2019


Monday, June 17, 2019


Monday, June 3, 2019

Presenter: Scott Bauer

Topic: N-of-1 deprescribing RCT protocol

Monday, May 20, 2019

Presenter: Rebecca Scherzer

Topic: On statistical significance and the p-value fallacy

Suggested Readings:

Amrhein  V, Greenland  S, McShane  B.  Scientists rise up against statistical significance.  Nature. 2019;567(7748):305-307. doi:

Ioannidis JPA. The Importance of Predefined Rules and Prespecified Statistical Analyses: Do Not Abandon Significance. JAMA. Published online April 04, 2019. doi:10.1001/jama.2019.4582

Bacchetti, Peter.  "Common Biostatistical Problems and the Best Practices that Prevent Them".  Available from:

Monday, May 6 , 2019

Presenter: Michelle Estrella

Topic: OPTICS study update

Monday, April 22 , 2019

Presenter: Meyeon Park

Topic: Practice presentation for NKF 

Monday, April 8, 2019

Presenter: Michael Shlipak, Michelle Estrella

Topic: KHRC update

Monday, March 25, 2019

Presenter: Michelle Estrella

Topic: TBD

Monday, March 11, 2019


Monday, February 25, 2019

Presenter: Vasantha Jotwani

Topic: Mitochondrial Health, Cardiovascular Health and Frailty in SPRINT

Monday, February 11, 2019

Presenter: Michelle Estrella

Topic: TBD

Monday, January 28, 2019

Presenter: LekhaTummalapalli

Topic: CKD Awareness project and REGARDS cohort ideas

Monday, December 17, 2018

Presenter: Scott Bauer

Monday, December 3, 2018

Presenter: Meyeon Park

Monday, October 22, 2018

Presenter: Simon Ascher

Monday, September 24, 2018

Presenter: Lekha Tummalapalli

Topic: Cardiac Biomarkers are Associated with Heart Failure Symptom Scores in the Chronic Renal Insufficiency Cohort (CRIC)

Monday, August 27, 2018

Presenter: All members

Topic: Updates from everyone

Summer Break- No WIPS in June-August 2018

Monday, June 4, 2018

Presenter: Michelle Estrella and Anthony Muiru

Topic: Potential projects in H3Africa

Monday, May 28, 2018

Memorial Day- NO KHRC WIP

Monday, May 14, 2018

Presenter: Brian Chan, Carmen Peralta, and Michelle Estrella

Topic: Using Epic data for research

Monday, May 7, 2018 (we will not have WIP April 30, 2018)

Presenter: Carmen Peralta

Topic: From epidemiology to trials: health services research in CKD

Monday, April 16, 2018

Presenter: Meyeon Park

Topic: MRI and biopsy study data and paper presentation

Monday, April 9, 2018

Presenter: Alex Lee

Topic: SPRINT biomarker results to date

Monday, March 19, 2018

Presenter: Mike Shlipak

Topic: new R01 Aims

Monday, March 5, 2018

Presenter: Vighnesh Walavalkar

Topic: Introduction to renal pathology, histology, and glomerular and interstitial disease.

Monday, February 29, 2018


President's Day holiday

Monday, February 5, 2018

Presenter: All members

Topic: updates on work from all members

Monday, January 22, 2018


Monday, January 8, 2018

Presenter: Michael Shlipak and Michelle Estrella

Topic: new R01 Aims

Monday, December 25, 2017


Happy Holidays!

Monday, December 11, 2017

Presenter: Raymond Hsu and Anna Rubinsky

Topic: Data from "Clinical Outcomes after Dialysis-Requiring Acute Kidney Injury"- R03 study (PI: Hsu)

Monday, November 27, 2017

Presenter: Meyeon Park

Topic: Doris Duke Medical Student mentoring project application

Monday, November 13, 2017

Presenter: Carmen Peralta and Michelle Estrella

Topic: R01 proposed Aims for new upcoming grant submission

Monday, October 30, 2017

Presenter: Lenny Lopez and Carmen Peralta

Topic: R01 proposed Aims for new upcoming grant submission

Monday, October 16, 2017

Presenter: Anthony Muiru

Topic: K23 proposed Aims

Monday, October 2, 2017

Presenter: Meyeon Park

Topic: Progress report/presentation on Doris Duke award project

Monday, August 21, 2017

Presenter: Vasantha Jotwani

Topic: Using new trauma cohort through the Department of Medicine's cohort development grant- study design help.

Tuesday, August 1st, 2017

Presenter: Martin Frigaard

Topic: Associations of CKD diagnosis in a chart and the processes of care that follow.

Tuesday, July 4th, 2017

No KHRC WIP due to the Federal Holiday

Tuesday, June 20th, 2017

Presenter: Carmen Peralta and Anna Rubsinky

Topic: How to handle blood pressure outcome in Dr. Peralta's VA clinical trial

Tuesday, June 6, 2017

Presenter: KHRC group

Topic: ASN abstract submission presentations

Tuesday, May 23rd, 2017

Presenter: Carmen Peralta and Michelle Estrella

Topic: Brainstorming on APOL1 genotype grant submission

Tuesday, May 9th, 2017

Presenter: Jesse Ikeme and Vasantha Jotwani

Topic: updates on Ikeme paper and presentation on bridging UCSF with industry.

Useful links:


Tuesday, April 25th, 2017

WIP cancelled this week

Tuesday, April 11, 2017

Presenter: Vasantha Jotwani

Topic: mitochondrial DNA and kidney disease

Tuesday, March 28th, 2017

Presenter: Jesse Ikeme

Topic: Analyses of Randomized Clinical Trial for the Effect of Clopidogrel Added to Aspirin on Kidney Functio

Tuesday, March 14th, 2017

Presenter: Harini Sarathy

Topic: Analysis of the Hispanic Communities Healthy Study/Study of Latinos (SOL)

Tuesday, February 28th, 2017

Presenter(s): Michael Shlipak and Rebecca Scherzer

Topics: Association of FGF-23 with CVD Events, HF Events, and Mortality in SPRINT Participants with CKD and new analyses results from HIV biomarker studies